描述

3D bioprinted human cortical neural constructs derived from induced pluripotent stem cells
Salaris F, Colosi C, Brighi C, Soloperto A, Turris V, Benedetti MC, Ghirga S, Rosito M, Di Angelantonio S, Rosa A.
J Clin Med, 8(10). pii: E1595 (2019)

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L.
Nat Commun, 10(1):3304 (2019)

Possible implication of the CA2 hippocampal circuit in social cognition deficits observed in the neuroligin 3 knock-out mouse, a non-syndromic animal model of autism
Modi B, Pimpinella D, Pazienti A, Zacchi P, Cherubini E, Griguoli M.
Front Psychiatry, 10:513 (2019)

Anterior-enriched filopodia create the appearance of asymmetric membrane microdomains in polarizing C. elegans zygotes
Hirani N, Illukkumbura R, Bland T, Mathonnet G, Suhner D, Reymann AC, Goehring NW.
J Cell Sci, 132: jcs230714 (2019)

Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy
Nash CA, Wei W, Irannejad R, Smrcka AV.
Elife, 8. pii: e48167 (2019)

Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes
Colicino EG, Stevens K, Curtis E, Rathbun L, Bates M, Manikas J, Amack J, Freshour J, Hehnly H.
Mol Biol Cell, 30(13):1598-1609 (2019)

Neuroinflammatory processes, A1 astrocyte activation and protein aggregation in the retina of Alzheimer’s disease patients, possible biomarkers for early diagnosis
Grimaldi A, Pediconi N, Oieni F, Pizzarelli R, Rosito M, Giubettini M, Santini T, Limatola C, Ruocco G, Ragozzino D, Di Angelantonio S.
Front Neurosci, 13:925 (2019)

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics
O’Reilly MW, Westgate CS, Hornby C, Botfield H, Taylor AE, Markey K, Mitchell JL, Scotton WJ, Mollan SP, Yiangou A, Jenkinson C, Gilligan LC, Sherlock M, Gibney J, Tomlinson JW, Lavery GG, Hodson DJ, Arlt W, Sinclair AJ.
JCI Insight, 4(6). pii: 125348 (2019)

ATP synthase c-subunit-deficient mitochondria have a small cyclosporine a-sensitive channel, but lack the permeability transition pore
Neginskaya MA, Solesio ME, Berezhnaya EV, Amodeo GF, Mnatsakanyan N, Jonas EA, Pavlov EV.
Cell Rep, 26(1):11-17.e2 (2019)

Effective glucose uptake by human astrocytes requires its sequestration in the endoplasmic reticulum by glucose-6-phosphatase-β
Müller MS, Fouyssac M, Taylor CW.
Curr Biol, 28(21):3481-3486 (2018)

Huaier augmented the chemotherapeutic sensitivity of oxaliplatin via downregulation of YAP in hepatocellular carcinoma
Tao Y, Shan L, Xu X, Jiang H, Chen R, Qian Z, Yang Z, Liang B, Zheng H, Cai F, Yu Y, Ma L.
J Cancer, 9(21):3962-3970 (2018)

Spinning-disc confocal microscopy in the second near-infrared window (NIR-II)
Zubkovs V, Antonucci A, Schuergers N, Lambert B, Latini A, Ceccarelli R, Santinelli A, Rogov A, Ciepielewski D, Boghossian AA.
Sci Rep, 8(1):13770 (2018)

Medium throughput breathing human primary cell alveolus-on-chip model
Stucki JD, Hobi N, Galimov A, Stucki AO, Schneider-Daum N, Lehr CM, Huwer H, Frick M, Funke-Chambour M, Geiser T, Guenat OT.
Sci Rep, 8(1):14359 (2018)

A microfluidic platform for lifelong high-resolution and high throughput imaging of subtle aging phenotypes in C. elegans
Saberi-Bosari S, Huayta J, San-Miguel A.
Lab Chip, 18(20):3090-3100 (2018)

Guard cells in fern stomata are connected by plasmodesmata, but control cytosolic Ca2+ levels autonomously
Voss LJ, McAdam SAM, Knoblauch M, Rathje JM, Brodribb T, Hedrich R, Roelfsema MRG.
New Phytol, 219(1):206-215 (2018)

Live-cell imaging reveals the dynamics and function of single-telomere TERRA molecules in cancer cells
Avogaro L, Querido E, Dalachi M, Jantsch MF, Chartrand P, Cusanelli E.
RNA Biol, 15(6):787-796 (2018)

A novel multisite confocal system for rapid Ca2+ imaging from submicron structures in brain slices
Filipis L, Ait Ouares K, Moreau P, Tanese D, Zampini V, Latini A, Bleau C, Bleau C, Graham J, Canepari M.
J Biophotonics, 11(3) (2018)

Cholesterol modulates the cellular localization of Orai1 channels and its disposition among membrane domains
Bohórquez-Hernández A, Gratton E, Pacheco J, Asanov A, Vaca L.
Biochim Biophys Acta Mol Cell Biol Lipids, 1862(12):1481-1490 (2017)

Microscopic analysis of lysosomal membrane permeabilization
Giraldo AMV, Öllinger K, Loitto V.
Methods Mol Biol, 1594:73-92 (2017)

Temporal regulation of gap junctional communication between tenocytes subjected to static tensile strain with physiological and non-physiological amplitudes
Eijiro M, Haicheng P, Toshiro O.
Biochem Biophys Res Commun, 482(4):1170-1175 (2017)

RAMP2 influences glucagon receptor pharmacology via trafficking and signaling
Cegla J, Jones BJ, Gardiner JV, Hodson DJ, Marjot T, McGlone ER, Tan TM, Bloom SR.
Endocrinology, 158(8):2680-2693 (2017)

Effective modification of cell death-inducing intracellular peptides by means of a photo-cleavable peptide array-based screening system
Kozaki I, Shimizu K, Honda H.
J Biosci Bioeng, 124(2):209-214 (2017)

Multiple isoforms of nesprin1 are integral components of ciliary rootlets
Potter C, Zhu W, Razafsky D, Ruzycki P, Kolesnikov AV, Doggett T, Kefalov VJ, Betleja E, Mahjoub MR, Hodzic D.
Curr Biol, 27(13):2014-2022.e6 (2017)

Enhanced gap junction intercellular communication inhibits catabolic and pro-inflammatory responses in tenocytes against heat stress
Maeda E, Kimura S, Yamada M, Tashiro M, Ohashi T.
Journal of Cell Commun Signal, 11(4):369-380 (2017)

Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway
Quaranta R, Pelullo M, Zema S, Nardozza F1, Checquolo S, Lauer DM, Bufalieri F, Palermo R, Felli MP, Vacca A, Talora C, Di Marcotullio L, Screpanti I, Bellavia D
Cell Death Dis, 8(7): e2942 (2017)

Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins
Tkatch T, Greotti E, Baranauskas G, Pendin D, Roy S, Nita LI, Wettmarshausen J, Prigge M, Yizhar O, Shirihai OS, Fishman D, Hershfinkel M, Fleidervish IA, Perocchi F, Pozzan T, Sekler I.
Proc Natl Acad Sci U S A, 114(26):E5167-E5176 (2017)

ATP release during cell swelling activates a Ca2+-dependent Cl- current by autocrine mechanism in mouse hippocampal microglia
Murana E, Pagani F, Basilico B, Sundukova M, Batti L, Di Angelantonio S, Cortese B, Grimaldi A, Francioso A, Heppenstall P, Bregestovski P, Limatola C, Ragozzino D.
Sci Rep, 7(1):4184 (2017)

Remote control of glucose homeostasis in vivo using photopharmacology
Mehta ZB, Johnston NR, Nguyen-Tu MS, Broichhagen J, Schultz P, Larner DP, Leclerc I, Trauner D, Rutter GA, Hodson DJ.
Sci Rep, 7(1):291 (2017)

Peri-synaptic glia recycles brain-derived neurotrophic factor for LTP stabilization and memory retention
Vignoli B, Battistini G, Melani R, Blum R, Santi S, Berardi N, Canossa M.
Neuron, 92(4):873-887 (2016)

Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate
Huethorst E, Hortigon M, Zamora-Rodriguez V, Reynolds PM, Burton F, Smith G, Gadegaard N.
ACS Biomater Sci Eng, 2(12):2231-2239 (2016)

The circadian clock modulates anti-cancer properties of curcumin
Sarma A, Sharma VP, Sarkar AB, Sekar MC, Samuel K, Geusz ME.
BMC Cancer, 16(1):759 (2016)

Circadian rhytms in doxorubicin nuclear uptake and clock control of C6 glioma cells
Sarma A, Sharma VP, Geusz ME.
J Cancer Ther, Vol.7 Num.8 (2016)

Localized down-regulation of P-glycoprotein by focused ultrasound and microbubbles induced blood-brain barrier disruption in rat brain
HongSeok C, Hwa-Youn L, Mun H, Jong-ryul C, Sanghyun A, Taekwan L, Yongmin C, Juyoung P.
Sci Rep, 6:31201 (2016)

Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases
Lenzi J, Pagani F, De Santis R, Limatola C, Bozzoni I, Di Angelantonio S, Rosa S.
Stem Cell Res, 17(1):140-7 (2016)

Current injection provokes rapid expansion of the guard cell cytosolic volume and triggers Ca(2+) signals
Voss LJ, Hedrich R, Roelfsema MRG.
Mol Plant, 9(3):471-480 (2016)

Spatiotemporal profiles of arginine vasopressin transcription in cultured suprachiasmatic nucleus
Yoshikawa T, Nakajima Y, Yamada Y, Enoki R, Watanabe K, Yamazaki M, Sakimura K, Honma S, Honma K.
Eur J Neurosci, 42(9):2678-89 (2015)

The Zinc transporter Slc30a8/ZnT8 is required in a subpopulation of pancreatic α-cells for hypoglycemia-induced glucagon secretion
Solomou A, Meur G, Bellomo E, Hodson DJ, Tomas A, Li SM, Philippe E, Herrera PL, Magnan C, Rutter GA.
J Biol Chem, 290(35):21432-42 (2015)

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons
Lenzi J, De Santis R, de Turris V, Morlando M, Laneve P, Calvo A, Caliendo V, Chiò A, Rosa A, Bozzoni I.
Dis Model Mech, 8(7):755-66 (2015)

Development of circadian oscillators in neurosphere cultures during adult neurogenesis
Malik A, Jamasbi RJ, Kondratov RV, Geusz ME.
PLoS One, 10(3):e0122937 (2015)

Chlamydia infection depends on a functional MDMM2-p53 axis
González E, Rother M, Kerr MC, Al-Zeer MA, Abu-Lubad M, Kessler M, Brinkmann V, Loewer A, Meyer TF.
Nat Commun, 5: 5201 (2014)

Interchromosomal homology searches drive directional ALT telomere movement and synapsis
Cho NW, Dilley RL, Lampson MA., Greenberg RA.
Cell, 159(1):108-121 (2014)

Early events of fertilization in sea urchin eggs are sensitive to actin-binding organic molecules
Chun JT, Limatola N, Vasilev F, Santella L.
Biochem Biophys Res Commun, 450 (3), 1166-1174 (2014)

Phosphoinositides and membrane curvature switch the mode of actin polymerization via selective recruitment of toca-1 and Snx9
Gallop JL, Walrantb A, Cantleya LC, Kirschnera MW.
Proc Natl Acad Sci U S A, 110(18):7193-8 (2013)